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The Significance of Mitochondrial Dysfunction in Cancer

As an essential organelle in nucleated eukaryotic cells, mitochondria play a central role in energy metabolism, maintenance of redox balance, and regulation of apoptosis. Mitochondrial dysfunction, either due to the TCA cycle enzyme defects, mitochondrial DNA genetic mutations, defective mitochondri...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Luo, Yongde, Ma, Jianjia, Lu, Weiqin
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460667/
https://ncbi.nlm.nih.gov/pubmed/32764295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165598
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