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Novel therapeutic strategies targeting HIV integrase

Integration of the viral genome into host cell chromatin is a pivotal and unique step in the replication cycle of retroviruses, including HIV. Inhibiting HIV replication by specifically blocking the viral integrase enzyme that mediates this step is an obvious and attractive therapeutic strategy. Aft...

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Detalhes bibliográficos
Main Authors: Quashie, Peter K, Sloan, Richard D, Wainberg, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348091/
https://ncbi.nlm.nih.gov/pubmed/22498430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-10-34
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