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Prospective strategies for targeting HIV-1 integrase function

Integration is a key step in the HIV-1 life cycle in which the ends of linear viral DNA are covalently joined with host chromosomal DNA. Integrase is the highly conserved and essential viral protein that performs two catalytically related reactions that ultimately lead to the insertion of the viral...

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Dettagli Bibliografici
Autori principali: Luo, Yang, Muesing, Mark A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045043/
https://ncbi.nlm.nih.gov/pubmed/21359091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.10.205
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