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The Role of Lysine 186 in HIV-1 Integrase Multimerization
HIV-1 integrase (IN) catalyzes biochemical reactions required for viral cDNA insertion into host cell chromosomal DNA, an essential step in the HIV-1 replication cycle. In one of these reactions, the two ends of the linear viral cDNA are believed to be simultaneously ligated to chromosomal DNA by a...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2149894/ https://ncbi.nlm.nih.gov/pubmed/17397894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.02.029 |
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