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Complementation of integrase function in HIV-1 virions.

Proviral integration is essential for HIV-1 replication and represents an important potential target for antiviral drug design. Although much is known about the integration process from studies of purified integrase (IN) protein and synthetic target DNA, provirus formation in virally infected cells...

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Main Authors: Fletcher, T M, Soares, M A, McPhearson, S, Hui, H, Wiskerchen, M, Muesing, M A, Shaw, G M, Leavitt, A D, Boeke, J D, Hahn, B H
格式: Artigo
語言:Inglês
出版: 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170146/
https://ncbi.nlm.nih.gov/pubmed/9305653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.16.5123
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