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Complementation of integrase function in HIV-1 virions.

Proviral integration is essential for HIV-1 replication and represents an important potential target for antiviral drug design. Although much is known about the integration process from studies of purified integrase (IN) protein and synthetic target DNA, provirus formation in virally infected cells...

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Dettagli Bibliografici
Autori principali: Fletcher, T M, Soares, M A, McPhearson, S, Hui, H, Wiskerchen, M, Muesing, M A, Shaw, G M, Leavitt, A D, Boeke, J D, Hahn, B H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170146/
https://ncbi.nlm.nih.gov/pubmed/9305653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.16.5123
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