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Nucleotide Pocket Thermodynamics Measured by EPR Reveal How Energy Partitioning Relates Speed to Efficiency
We have used spin-labeled ADP to investigate the dynamics of the nucleotide-binding pocket in a series of myosins, which have a range of velocities. Electron Paramagnetic Resonance spectroscopy reveals that the pocket is in an equilibrium between open and closed conformations. In the absence of acti...
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Main Authors: | , , , , , , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
2010
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347976/ https://ncbi.nlm.nih.gov/pubmed/21185304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.053 |
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