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The Extended Cell Panel Assay Characterizes the Relationship of Prion Strains RML, 79A, and 139A and Reveals Conversion of 139A to 79A-Like Prions in Cell Culture

Three commonly used isolates of murine prions, 79A, 139A, and RML, were derived from the so-called Chandler isolate, which was obtained by propagating prions from scrapie-infected goat brain in mice. RML is widely believed to be identical with 139A; however, using the extended cell panel assay (ECPA...

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Hlavní autoři: Oelschlegel, Anja M., Fallahi, Mohammad, Ortiz-Umpierre, Shannon, Weissmann, Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347355/
https://ncbi.nlm.nih.gov/pubmed/22379091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00181-12
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