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Attenuated Influenza Virus Construct with Enhanced Hemagglutinin Protein Expression
Influenza A viruses encoding an altered viral NS1 protein have emerged as promising live attenuated vaccine platforms. A carboxy-terminal truncation in the NS1 protein compromises its interferon antagonism activity, making these viruses attenuated in the host yet still able to induce protection from...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347287/ https://ncbi.nlm.nih.gov/pubmed/22398291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00190-12 |
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