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Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange

Most spontaneous DNA double-strand breaks (DSBs) arise during replication and are repaired by homologous recombination (HR) with the sister chromatid. Many proteins participate in HR, but it is often difficult to determine their in vivo functions due to the existence of alternative pathways. Here we...

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Hlavní autoři: Muñoz-Galván, Sandra, Tous, Cristina, Blanco, Miguel G., Schwartz, Erin K., Ehmsen, Kirk T., West, Stephen C., Heyer, Wolf-Dietrich, Aguilera, Andrés
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347241/
https://ncbi.nlm.nih.gov/pubmed/22354996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00111-12
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