In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies
A major concern associated with the use of vaccines based on live-attenuated viruses is the possible and well documented reversion to pathogenic phenotypes. In the case of HIV, genomic deletions or mutations introduced to attenuate viral pathogenicity can be repaired by selection of compensating mut...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11353837/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.111031498 |
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