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The Plausibility of RNA-Templated Peptides: Simultaneous RNA Affinity for Adjacent Peptide Side Chains

According to the RNA world hypothesis, coded peptide synthesis (translation) must have been first catalyzed by RNAs. Here, we show that small RNA sequences can simultaneously bind the dissimilar amino acids His and Phe in peptide linkage. We used in vitro counterselection/selection to isolate a pool...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Turk-MacLeod, Rebecca M., Puthenvedu, Deepa, Majerfeld, Irene, Yarus, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer-Verlag 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346935/
https://ncbi.nlm.nih.gov/pubmed/22538927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00239-012-9501-8
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