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Selection of the simplest RNA that binds isoleucine

We have identified the simplest RNA binding site for isoleucine using selection-amplification (SELEX), by shrinking the size of the randomized region until affinity selection is extinguished. Such a protocol can be useful because selection does not necessarily make the simplest active motif most pro...

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Bibliografske podrobnosti
Main Authors: LOZUPONE, CATHERINE, CHANGAYIL, SHANKAR, MAJERFELD, IRENE, YARUS, MICHAEL
Format: Artigo
Jezik:Inglês
Izdano: Copyright 2003 by RNA Society 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287053/
https://ncbi.nlm.nih.gov/pubmed/14561881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5114503
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