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The Plausibility of RNA-Templated Peptides: Simultaneous RNA Affinity for Adjacent Peptide Side Chains

According to the RNA world hypothesis, coded peptide synthesis (translation) must have been first catalyzed by RNAs. Here, we show that small RNA sequences can simultaneously bind the dissimilar amino acids His and Phe in peptide linkage. We used in vitro counterselection/selection to isolate a pool...

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Detaylı Bibliyografya
Asıl Yazarlar: Turk-MacLeod, Rebecca M., Puthenvedu, Deepa, Majerfeld, Irene, Yarus, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer-Verlag 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346935/
https://ncbi.nlm.nih.gov/pubmed/22538927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00239-012-9501-8
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