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Cross-backbone templating; ribodinucleotides made on poly(C)

G(5′)pp(5′)G synthesis from pG and chemically activated 2MeImpG is accelerated by the addition of complementary poly(C), but affected only slightly by poly(G) and not at all by poly(U) and poly(A). This suggests that 3′–5′ poly(C) is a template for uncatalyzed synthesis of 5′–5′ GppG, as was poly(U)...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Majerfeld, Irene, Puthenvedu, Deepa, Yarus, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748817/
https://ncbi.nlm.nih.gov/pubmed/26759450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.054866.115
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