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Cross-backbone templating; ribodinucleotides made on poly(C)

G(5′)pp(5′)G synthesis from pG and chemically activated 2MeImpG is accelerated by the addition of complementary poly(C), but affected only slightly by poly(G) and not at all by poly(U) and poly(A). This suggests that 3′–5′ poly(C) is a template for uncatalyzed synthesis of 5′–5′ GppG, as was poly(U)...

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: Majerfeld, Irene, Puthenvedu, Deepa, Yarus, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748817/
https://ncbi.nlm.nih.gov/pubmed/26759450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.054866.115
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