KRAS, BRAF and PIK3CA Mutations and the Loss of PTEN Expression in Chinese Patients with Colorectal Cancer

BACKGROUND: To investigate the frequency and relationship of the KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer (CRC). METHODOLOGY/PRINCIPAL FINDINGS: Genomic DNA was extracted from the formalin-fixed paraffin-embedded (FFPE) tissues of 69...

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Bibliografiske detaljer
Main Authors: Mao, Chen, Zhou, Junhua, Yang, Zuyao, Huang, Yafang, Wu, Xinyin, Shen, Hong, Tang, Jinling, Chen, Qing
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346734/
https://ncbi.nlm.nih.gov/pubmed/22586484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036653
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