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Concordant analysis of KRAS, BRAF, PIK3CA mutations, and PTEN expression between primary colorectal cancer and matched metastases

Current data on the concordance of KRAS, BRAF, PIK3CA mutation status or PTEN expression status between primary tumors and metastases in colorectal cancer (CRC) are conflicting. We conducted a systematic review and meta-analysis to examine concordance and discordance of the status of these four biom...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mao, Chen, Wu, Xin-Yin, Yang, Zu-Yao, Threapleton, Diane Erin, Yuan, Jin-Qiu, Yu, Yuan-Yuan, Tang, Jin-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648436/
https://ncbi.nlm.nih.gov/pubmed/25639985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08065
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