Standardized Comparison of the Relative Impacts of HIV-1 Reverse Transcriptase (RT) Mutations on Nucleoside RT Inhibitor Susceptibility

Determining the phenotypic impacts of reverse transcriptase (RT) mutations on individual nucleoside RT inhibitors (NRTIs) has remained a statistical challenge because clinical NRTI-resistant HIV-1 isolates usually contain multiple mutations, often in complex patterns, complicating the task of determ...

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Hlavní autoři: Melikian, George L., Rhee, Soo-Yon, Taylor, Jonathan, Fessel, W. Jeffrey, Kaufman, David, Towner, William, Troia-Cancio, Paolo V., Zolopa, Andrew, Robbins, Gregory K., Kagan, Ron, Israelski, Dennis, Shafer, Robert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346663/
https://ncbi.nlm.nih.gov/pubmed/22330916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05487-11
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