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Saquinavir Inhibits the Malaria Parasite's Chloroquine Resistance Transporter

The antiretroviral protease inhibitors (APIs) ritonavir, saquinavir, and lopinavir, used to treat HIV infection, inhibit the growth of Plasmodium falciparum at clinically relevant concentrations. Moreover, it has been reported that these APIs potentiate the activity of chloroquine (CQ) against this...

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書誌詳細
主要な著者: Martin, Rowena E., Butterworth, Alice S., Gardiner, Donald L., Kirk, Kiaran, McCarthy, James S., Skinner-Adams, Tina S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346596/
https://ncbi.nlm.nih.gov/pubmed/22354298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00166-12
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