Molecular Basis of Requirement of Receptor Activator of Nuclear Factor κB Signaling for Interleukin 1-mediated Osteoclastogenesis

IL-1, a proinflammatory cytokine, is implicated in bone loss in various pathological conditions by promoting osteoclast formation, survival, and function. Although IL-1 alone can sufficiently prolong osteoclast survival and activate osteoclast function, IL-1-mediated osteoclastogenesis requires the...

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Detalhes bibliográficos
Main Authors: Jules, Joel, Zhang, Ping, Ashley, Jason W., Wei, Shi, Shi, Zhenqi, Liu, Jianzhong, Michalek, Suzanne M., Feng, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346127/
https://ncbi.nlm.nih.gov/pubmed/22416138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.296228
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