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Mononuclear Iron Enzymes Are Primary Targets of Hydrogen Peroxide Stress
This study tested whether nonredox metalloenzymes are commonly charged with iron in vivo and are primary targets of oxidative stress because of it. Indeed, three sample mononuclear enzymes, peptide deformylase, threonine dehydrogenase, and cytosine deaminase, were rapidly damaged by micromolar hydro...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3346116/ https://ncbi.nlm.nih.gov/pubmed/22411989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.330365 |
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