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Iron enzyme ribulose-5-phosphate 3-epimerase in Escherichia coli is rapidly damaged by hydrogen peroxide but can be protected by manganese

H(2)O(2) is commonly generated in biological habitats by environmental chemistry and by cellular immune responses. H(2)O(2) penetrates cells, disrupts metabolism, and blocks growth; it therefore is of interest to identify the major cellular molecules that H(2)O(2) damages and the strategies by which...

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Detalhes bibliográficos
Main Authors: Sobota, Jason M., Imlay, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069151/
https://ncbi.nlm.nih.gov/pubmed/21402925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100410108
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