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Intracellular Hydrogen Peroxide and Superoxide Poison 3-Deoxy-d-Arabinoheptulosonate 7-Phosphate Synthase, the First Committed Enzyme in the Aromatic Biosynthetic Pathway of Escherichia coli
In Escherichia coli, aromatic compound biosynthesis is the process that has shown the greatest sensitivity to hydrogen peroxide stress. This pathway has long been recognized to be sensitive to superoxide as well, but the molecular target was unknown. Feeding experiments indicated that the bottleneck...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010980/ https://ncbi.nlm.nih.gov/pubmed/24659765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01573-14 |
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