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Superoxide poisons mononuclear iron enzymes by causing mismetallation
Superoxide (O(2)(−)) is a primary agent of intracellular oxidative stress. Genetic studies in many organisms have confirmed that excess O(2)(−) disrupts metabolism, but to date only a small family of [4Fe-4S] dehydratases have been identified as direct targets. This investigation reveals that in Esc...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731988/ https://ncbi.nlm.nih.gov/pubmed/23678969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12263 |
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