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Calpain 2 Regulates Akt-FoxO-p27(Kip1) Protein Signaling Pathway in Mammary Carcinoma
We investigated the role of the ubiquitously expressed calpain 2 isoform in breast tumor cell growth, migration, signaling, and tumorigenesis. RNAi-mediated knockdown of the capn2 transcript was used to manipulate expression of the catalytic subunit of calpain 2 in the AC2M2 mouse mammary carcinoma...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3346101/ https://ncbi.nlm.nih.gov/pubmed/22427650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.349308 |
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