The Akt/FoxO/p27(Kip1) axis contributes to the anti‐proliferation of pentoxifylline in hypertrophic scars

Hypertrophic scars (HS) are characterized by the excessive production and deposition of extracellular matrix (ECM) proteins. Pentoxifylline (PTX), a xanthine derived antioxidant, inhibits the proliferation, inflammation and ECM accumulation of HS. In this study, we aimed to explore the effect of PTX...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Yang, Fangfang, Chen, Erfei, Yang, Yunshu, Han, Fu, Han, Shichao, Wu, Gaofeng, Zhang, Min, Zhang, Jian, Han, Juntao, Su, Linlin, Hu, Dahai
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714140/
https://ncbi.nlm.nih.gov/pubmed/31270945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14498
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