Oligodendrocyte Regeneration after Neonatal Hypoxia Requires FoxO1-Mediated p27(Kip1) Expression

Diffuse white matter injury (DWMI) caused by hypoxia is associated with permanent neurodevelopmental disabilities in preterm infants. The cellular and molecular mechanisms producing DWMI are poorly defined. Using a mouse model of neonatal hypoxia, we demonstrate a biphasic effect on oligodendrocyte...

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Detalhes bibliográficos
Main Authors: Jablonska, Beata, Scafidi, Joseph, Aguirre, Adan, Vaccarino, Flora, Nguyen, Vien, Borok, Erzsebet, Horvath, Tamas L., Rowitch, David H., Gallo, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517297/
https://ncbi.nlm.nih.gov/pubmed/23077062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2060-12.2012
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