Oligodendrocyte Regeneration after Neonatal Hypoxia Requires FoxO1-Mediated p27(Kip1) Expression

Diffuse white matter injury (DWMI) caused by hypoxia is associated with permanent neurodevelopmental disabilities in preterm infants. The cellular and molecular mechanisms producing DWMI are poorly defined. Using a mouse model of neonatal hypoxia, we demonstrate a biphasic effect on oligodendrocyte...

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Auteurs principaux: Jablonska, Beata, Scafidi, Joseph, Aguirre, Adan, Vaccarino, Flora, Nguyen, Vien, Borok, Erzsebet, Horvath, Tamas L., Rowitch, David H., Gallo, Vittorio
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2012
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517297/
https://ncbi.nlm.nih.gov/pubmed/23077062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2060-12.2012
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