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TGFβ Signaling Regulates the Timing of CNS Myelination by Modulating Oligodendrocyte Progenitor Cell Cycle Exit through SMAD3/4/FoxO1/Sp1

Research on myelination has focused on identifying molecules capable of inducing oligodendrocyte (OL) differentiation in an effort to develop strategies that promote functional myelin regeneration in demyelinating disorders. Here, we show that transforming growth factor β (TGFβ) signaling is crucial...

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書誌詳細
主要な著者: Palazuelos, Javier, Klingener, Michael, Aguirre, Adan
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044250/
https://ncbi.nlm.nih.gov/pubmed/24899714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0363-14.2014
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