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TGFβ Signaling Regulates the Timing of CNS Myelination by Modulating Oligodendrocyte Progenitor Cell Cycle Exit through SMAD3/4/FoxO1/Sp1

Research on myelination has focused on identifying molecules capable of inducing oligodendrocyte (OL) differentiation in an effort to develop strategies that promote functional myelin regeneration in demyelinating disorders. Here, we show that transforming growth factor β (TGFβ) signaling is crucial...

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Bibliografiske detaljer
Main Authors: Palazuelos, Javier, Klingener, Michael, Aguirre, Adan
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044250/
https://ncbi.nlm.nih.gov/pubmed/24899714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0363-14.2014
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