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Plasma Membrane Potential Oscillations in Insulin Secreting Ins-1 832/13 Cells Do Not Require Glycolysis and Are Not Initiated by Fluctuations in Mitochondrial Bioenergetics

Oscillations in plasma membrane potential play a central role in glucose-induced insulin secretion from pancreatic β-cells and related insulinoma cell lines. We have employed a novel fluorescent plasma membrane potential (Δψ(p)) indicator in combination with indicators of cytoplasmic free Ca(2+) ([C...

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Autors principals: Goehring, Isabel, Gerencser, Akos A., Schmidt, Sara, Brand, Martin D., Mulder, Hindrik, Nicholls, David G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346073/
https://ncbi.nlm.nih.gov/pubmed/22418435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.314567
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