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Cell Fate Control Gene Therapy Based on Engineered Variants of Human Deoxycytidine Kinase

The safety of cell therapy applications can be enhanced by the introduction of Cell Fate Control (CFC) elements, which encode pharmacologically controlled cellular suicide switches. CFC Gene Therapy (CFCGT) offers the possibility of establishing control over gene-modified cells (GMCs) with regards t...

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Библиографические подробности
Главные авторы: Neschadim, Anton, Wang, James CM, Sato, Takeya, Fowler, Daniel H, Lavie, Arnon, Medin, Jeffrey A
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345984/
https://ncbi.nlm.nih.gov/pubmed/22273576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.298
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