Llwytho...

Harnessing autophagy for cell fate control gene therapy

We hypothesized that rapamycin, through induction of autophagy and promotion of an antiapoptotic phenotype, would permit lentiviral (LV)-based transgene delivery to human T-Rapa cells, which are being tested in phase II clinical trials in the setting of allogeneic hematopoietic cell transplantation....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Felizardo, Tania C., Foley, Jason, Steed, Kevin, Dropulic, Boro, Amarnath, Shoba, Medin, Jeffrey A., Fowler, Daniel H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722316/
https://ncbi.nlm.nih.gov/pubmed/23633667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24639
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