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Replication-competent Herpes Simplex Virus Retargeted to HER2 as Therapy for High-grade Glioma

Oncolytic herpes simplex viruses (HSVs) represent a novel frontier against tumors resistant to standard therapies, like glioblastoma (GBM). The oncolytic HSVs that entered clinical trials so far showed encouraging results; however, they are marred by the fact that they are highly attenuated. We engi...

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Detalhes bibliográficos
Main Authors: Gambini, Eleonora, Reisoli, Elisa, Appolloni, Irene, Gatta, Valentina, Campadelli-Fiume, Gabriella, Menotti, Laura, Malatesta, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345974/
https://ncbi.nlm.nih.gov/pubmed/22354378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.22
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