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Replication-competent Herpes Simplex Virus Retargeted to HER2 as Therapy for High-grade Glioma
Oncolytic herpes simplex viruses (HSVs) represent a novel frontier against tumors resistant to standard therapies, like glioblastoma (GBM). The oncolytic HSVs that entered clinical trials so far showed encouraging results; however, they are marred by the fact that they are highly attenuated. We engi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345974/ https://ncbi.nlm.nih.gov/pubmed/22354378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.22 |
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