Solid-phase synthesis of branched oligoribonucleotides related to messenger RNA splicing intermediates.
The chemical synthesis of oligoribonucleotides containing vicinal (2'-5')- and (3'-5')-phosphodiester linkages is described. The solid-phase method, based on silyl-phosphoramidite chemistry, was applied to the synthesis of a series of branched RNA [(Xp)nA2' (pN)n3'(pN)n] related to the splicing inte...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1992
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334572/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1480476/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.24.6565 |
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