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Modification of guanine bases by nucleoside phosphoramidite reagents during the solid phase synthesis of oligonucleotides.

Nucleoside 3'-phosphoramidite and chlorophosphite reagents have been found to react with the lactam function of guanine. This reaction caused unsatisfactory results when oligodeoxyribonucleotides containing a large number of guanine bases were prepared in an automated solid phase synthesizer. T...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pon, R T, Damha, M J, Ogilvie, K K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1985
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC321970/
https://ncbi.nlm.nih.gov/pubmed/4059050
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