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Repair synthesis by human cell extracts in cisplatin-damaged DNA is preferentially determined by minor adducts.

During reaction of cis-diamminedichloroplatinum(II) (cis-DDP) with DNA, a number of adducts are formed which may be discriminated by the excision-repair system. An in vitro excision-repair assay with human cell-free extracts has been used to assess the relative repair extent of monofunctional adduct...

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Bibliografische gegevens
Hoofdauteurs: Calsou, P, Frit, P, Salles, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC334528/
https://ncbi.nlm.nih.gov/pubmed/1475197
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