Structure of the human M(2) muscarinic acetylcholine receptor bound to an antagonist

The parasympathetic limb of the autonomic nervous system regulates the activity of multiple organ systems. Muscarinic receptors are G protein coupled receptors (GPCRs) that mediate the response to acetylcholine released from parasympathetic nerves.(1–5) Their role in the unconscious regulation of or...

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Main Authors: Haga, Kazuko, Kruse, Andrew C., Asada, Hidetsugu, Yurugi-Kobayashi, Takami, Shiroishi, Mitsunori, Zhang, Cheng, Weis, William I., Okada, Tetsuji, Kobilka, Brian K., Haga, Tatsuya, Kobayashi, Takuya
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345277/
https://ncbi.nlm.nih.gov/pubmed/22278061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10753
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