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Double strand binding – single strand incision mechanism for human flap endonuclease: implications for the superfamily
Detailed structural, mutational, and biochemical analyses of human FEN1/DNA complexes have revealed the mechanism for recognition of 5′ flaps formed during lagging strand replication and DNA repair. FEN1 processes 5′ flaps through a previously unknown, but structurally elegant double-stranded (ds) r...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345168/ https://ncbi.nlm.nih.gov/pubmed/22244820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.11.009 |
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