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Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages
There is accumulating evidence that the complement activation product, C5a, can orchestrate cellular immune functions. IL-27 (p28/EBI3) is an emerging key player essential for regulating inflammatory responses and T cells. Here, we report that C5a robustly suppressed IL-27(p28) gene expression and r...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345104/ https://ncbi.nlm.nih.gov/pubmed/22491257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102914 |
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