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C5a interaction with both C5aR and C5L2 receptors is required for production of G-CSF during the acute inflammatory response

The complement activation product, C5a, is a key factor for regulation of inflammatory responses. C5a and C5a(desArg) bind to their receptors, C5aR and C5L2, but the functional roles of C5L2 remain controversial. We screened the patterns of 23 inflammatory mediators in cultures of LPS-activated mous...

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Detalhes bibliográficos
Main Authors: Bosmann, Markus, Haggadone, Mikel D., Zetoune, Firas S., Sarma, J. Vidya, Ward, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795516/
https://ncbi.nlm.nih.gov/pubmed/23575697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243075
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