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Myeloid cell-derived HIF attenuates inflammation in UUO-induced kidney injury

Renal fibrosis and inflammation are associated with hypoxia, and tissue pO(2) plays a central role in modulating the progression of chronic kidney disease. Key mediators of cellular adaptation to hypoxia are hypoxia-inducible factor (HIF)-1 and -2. In the kidney they are expressed in a cell type-spe...

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Detalhes bibliográficos
Main Authors: Kobayashi, Hanako, Gilbert, Victoria, Liu, Qingdu, Kapitsinou, Pinelopi P., Unger, Travis L., Rha, Jennifer, Rivella, Stefano, Schlöndorff, Detlef, Haase, Volker H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345098/
https://ncbi.nlm.nih.gov/pubmed/22490864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103377
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