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Role of Zinc in Catalytic Activity of Carbonic Anhydrase IX

The carbonic anhydrases (CAs) in the α class are zinc-dependent metalloenzymes. Previous studies have reported that recombinant forms of carbonic anhydrase IX (CAIX), a membrane-bound form of CA expressed in solid tumors, appear to be activated by low levels of zinc independent of its well-studied r...

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Detalhes bibliográficos
Main Authors: Tu, Chingkuang, Foster, Lauren, Alvarado, Andrea, McKenna, Robert, Silverman, David N., Frost, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345035/
https://ncbi.nlm.nih.gov/pubmed/22465027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.03.017
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