Lysocardiolipin acyltransferase 1 (ALCAT1) controls mitochondrial DNA fidelity and biogenesis through modulation of MFN2 expression

Oxidative stress causes mitochondrial fragmentation and dysfunction in age-related diseases through unknown mechanisms. Cardiolipin (CL) is a phospholipid required for mitochondrial oxidative phosphorylation. The function of CL is determined by its acyl composition, which is significantly altered by...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Jia, Liu, Xiaolei, Wang, Huayan, Zhang, Weiping, Chan, David C., Shi, Yuguang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345005/
https://ncbi.nlm.nih.gov/pubmed/22509026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120043109
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