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Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor

β-Arrestins are multifunctional proteins that play central roles in G protein-coupled receptor (GPCR) trafficking and signaling. β-Arrestin1 is also recruited to the insulin-like growth factor-1 receptor (IGF-1R), a receptor tyrosine kinase (RTK), mediating receptor degradation and signaling. Becaus...

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Bibliografski detalji
Glavni autori: Zheng, Huiyuan, Worrall, Claire, Shen, Hongchang, Issad, Tarik, Seregard, Stefan, Girnita, Ada, Girnita, Leonard
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345003/
https://ncbi.nlm.nih.gov/pubmed/22509025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118359109
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