Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis

Although melanomas with mutant v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) can now be effectively targeted, there is no molecular target for most melanomas expressing wild-type BRAF. Here, we show that the activation of Pleckstrin homology domain-interacting protein (PHIP), promotes melano...

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Hlavní autoři: De Semir, David, Nosrati, Mehdi, Bezrookove, Vladimir, Dar, Altaf A., Federman, Scot, Bienvenu, Geraldine, Venna, Suraj, Rangel, Javier, Climent, Joan, Meyer Tamgüney, Tanja M., Thummala, Suresh, Tong, Schuyler, Leong, Stanley P. L., Haqq, Chris, Billings, Paul, Miller, James R., Sagebiel, Richard W., Debs, Robert, Kashani-Sabet, Mohammed
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344978/
https://ncbi.nlm.nih.gov/pubmed/22511720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119949109
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