Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis

Although melanomas with mutant v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) can now be effectively targeted, there is no molecular target for most melanomas expressing wild-type BRAF. Here, we show that the activation of Pleckstrin homology domain-interacting protein (PHIP), promotes melano...

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Bibliographische Detailangaben
Hauptverfasser: De Semir, David, Nosrati, Mehdi, Bezrookove, Vladimir, Dar, Altaf A., Federman, Scot, Bienvenu, Geraldine, Venna, Suraj, Rangel, Javier, Climent, Joan, Meyer Tamgüney, Tanja M., Thummala, Suresh, Tong, Schuyler, Leong, Stanley P. L., Haqq, Chris, Billings, Paul, Miller, James R., Sagebiel, Richard W., Debs, Robert, Kashani-Sabet, Mohammed
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344978/
https://ncbi.nlm.nih.gov/pubmed/22511720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119949109
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