Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis

Although melanomas with mutant v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) can now be effectively targeted, there is no molecular target for most melanomas expressing wild-type BRAF. Here, we show that the activation of Pleckstrin homology domain-interacting protein (PHIP), promotes melano...

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Detalhes bibliográficos
Main Authors: De Semir, David, Nosrati, Mehdi, Bezrookove, Vladimir, Dar, Altaf A., Federman, Scot, Bienvenu, Geraldine, Venna, Suraj, Rangel, Javier, Climent, Joan, Meyer Tamgüney, Tanja M., Thummala, Suresh, Tong, Schuyler, Leong, Stanley P. L., Haqq, Chris, Billings, Paul, Miller, James R., Sagebiel, Richard W., Debs, Robert, Kashani-Sabet, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344978/
https://ncbi.nlm.nih.gov/pubmed/22511720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119949109
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