Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis

Although melanomas with mutant v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) can now be effectively targeted, there is no molecular target for most melanomas expressing wild-type BRAF. Here, we show that the activation of Pleckstrin homology domain-interacting protein (PHIP), promotes melano...

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Bibliografiska uppgifter
Huvudupphovsmän: De Semir, David, Nosrati, Mehdi, Bezrookove, Vladimir, Dar, Altaf A., Federman, Scot, Bienvenu, Geraldine, Venna, Suraj, Rangel, Javier, Climent, Joan, Meyer Tamgüney, Tanja M., Thummala, Suresh, Tong, Schuyler, Leong, Stanley P. L., Haqq, Chris, Billings, Paul, Miller, James R., Sagebiel, Richard W., Debs, Robert, Kashani-Sabet, Mohammed
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344978/
https://ncbi.nlm.nih.gov/pubmed/22511720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119949109
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