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Blockade of T-Lymphocyte K(Ca)3.1 and K(v)1.3 Channels as Novel Immunosuppressive Strategy for Preventing Kidney Allograft Rejection
There currently is an unmet clinical need for novel immunosuppressants for the long-term prevention of kidney transplant rejection as alternatives to the nephrotoxic calcineurin inhibitor cyclosporine A (CsA). Recent studies show that K(+)-channels play a crucial role in T-lymphocyte activities. In...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343637/ https://ncbi.nlm.nih.gov/pubmed/19715983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2009.06.025 |
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