High-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex method

BACKGROUND: Aberrant DNA methylation leads to loss of heterozygosity (LOH) or loss of imprinting (LOI) as the first hit during human carcinogenesis. Recently we developed a new high-throughput, high-resolution DNA methylation analysis method, bisulphite PCR-Luminex (BPL), using sperm DNA and demonst...

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Autori principali: Hiura, Hitoshi, Okae, Hiroaki, Kobayash, Hisato, Miyauchi, Naoko, Sato, Fumi, Sato, Akiko, Suzuki, Fumihiko, Nagase, Satoru, Sugawara, Junichi, Nakai, Kunihiko, Yaegashi, Nobuo, Arima, Takahiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342152/
https://ncbi.nlm.nih.gov/pubmed/22443985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-5-8
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